In silico Protein Docking
Sunday, April 30
10 AM - 1:00 PM
In silico Protein Docking (Hands-on)Workshop
Instructors: Vinodh B. Kurella, Ph.D., Ph.D., Senior Scientist, Molecular Engineering Unit, Intexon Corp.
X-ray crystallography and Nuclear Magnetic Resonance (NMR) are the gold standards for deducing protein-protein interactions. These tools need elaborate infrastructure and time commitment at the least. Computational programs help save time and resources in the development of rational drug design against proteins. Recent advancements in computational power and crowd sourcing have led to creation of smarter machine learning algorithms such as Rosetta and games like Foldit. We will learn how to deduce protein-protein interactions (PPIs) using various computational methods such as Rosetta, GRAMM-X, Z-Dock and other commercial available programs.